Spoofing mac

Questions
1

When spoofing mac (via vbox settings)
Can i use any mac (as long as its in the hexadecimal format)
Ie: DA:4F:B2:8C:71:E5
And will this cause problems with anything?

2

New macsOS have spoofing capabilties available in settings:

For an old mac:

3

For a win11 vm, sorry for misconception