TUF A16 Advantage Edition? What a time to shine I’ve been researching this.
Right so as far as I know, unless Mint or Ubuntu has gotten the drivers, iirc the keyboard and trackpad doesnt work but they do work on a distro like arch and iirc Fedora works too.
Safe bet on both with one I would recommend as the safest bet being Bazzite since they have an asus ISO that would work out of the box very well.
https://forums.linuxmint.com/viewtopic.php?t=400080
here’s where I got the idea that it wouldnt exactly work on Ubuntu/Mint
This thread too
but if things have changed in a year or 2 later for ubuntu/debian then great but as far as research goes, Bazzite (or I guess generally Fedora) or Arch/EndeavourOS honestly. But if you can I would try a live cd and see if it works on Mint/Ubuntu and if not still then these 2
I hope that helps.